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Edward C. Halperin, MD, MA

  • Dean of the School of Medicine
  • Ford Foundation Professor of Medical Education
  • Professor of Radiation Oncology, Pediatrics, and History
  • University of Louisville
  • Louisville, Kentucky

Postoperative pulmonary complications after preoperative chemoradiation for esophageal carcinoma: correlation with pulmonary dose-volume histogram parameters prostate cancer awareness month cheap alfuzosin 10mg with mastercard. Propensity score-based comparison of long-term outcomes with 3-dimensional conformal radiotherapy vs man health and environment alfuzosin 10 mg. Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis prostate cancer odds proven alfuzosin 10mg. Women at increased risk for cardiac toxicity following chemoradiation therapy for esophageal carcinoma mens health 28 day fat torch review buy cheap alfuzosin 10 mg online. Investigation of clinical and dosimetric factors associated with postoperative pulmonary complications in esophageal cancer patients treated with concurrent chemoradiotherapy followed by surgery. Grade 3 late toxicity was experienced by 3 patients who developed small bowel obstruction. Grade 2 late toxicity was experienced by 3 patients: 1 with gastritis, 1 with esophagitis, and 1 with an ulcer. Limited advantages of intensity-modulated radiotherapy over 3D conformal radiation therapy in the adjuvant management of gastric cancer. Intensity-modulated radiation therapy with concurrent chemotherapy as preoperative treatment for localized gastric adenocarcinoma. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. Comparison of heart and coronary artery doses associated with intensitymodulated radiotherapy versus three-dimensional conformal radiotherapy for distal esophageal cancer. Treatment of high-risk gastric cancer postoperatively using intensity-modulated radiotherapy; a single-institution experience. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. Comparison of intensity-modulated radiotherapy and 3-dimensional conformal radiotherapy as adjuvant therapy for gastric cancer. Gastric surgical adjuvant radiotherapy consensus report: rationale and treatment implementation. Three-dimensional non-coplanar conformal radiotherapy yields better results than traditional beam arrangements for adjuvant treatment of gastric cancer. Intensity-modulated radiotherapy combined with chemotherapy for the treatment of gastric cancer patients after standard D1/D2 surgery. The use of neutron beam therapy is medically necessary in select cases of salivary gland tumors. Preoperative radiation therapy is considered medically necessary in select cases 1. Radiation may be given utilizing any of several schedules including conventional daily fractionation, concomitant boost accelerated fractionation, and hyperfractionation (twice-daily radiation) 3. Is medically necessary in unresected T2-4a, N0-3 cases utilizing up to 42 fractions with conventional schedule 2. Concurrent chemotherapy carries a high toxicity burden and requires substantial supportive care and the expertise of an experienced multidisciplinary team D. Is medically necessary for cases which have any of the following high risk factors: a. Vascular tumor embolism © 2019 eviCore healthcare. Re-irradiation may be indicated in cases of recurrent or persistent disease, or for in-field new primary tumors, in cases in which there are no known distant metastases B. When the goal of treatment is curative and surgery is not an option, reirradiation strategies can be considered for patients who: develop locoregional failures or second primaries at > 6 months after the initial radiotherapy; can receive additional doses of radiotherapy of at least 60 Gy; and can tolerate concurrent chemotherapy. Primary anatomic sites included in this category include paranasal sinuses (ethmoid and maxillary), salivary glands, the lip, oral cavity, oropharynx, hypopharynx, glottic larynx, supraglottic larynx, nasopharynx, and occult/unknown head and neck primary sites. Utilization of radiation therapy should be preceded by workup and staging, and planned in conjunction with the appropriate members of a multi-disciplinary team that also includes: diagnostic imaging, pathology, medical oncology; otorhinological, oral, plastic and reconstructive, neuro- and ophthalmologic surgeons; psychiatry; addiction services; audiology and speech therapy; rehabilitation and nutritional medicine; pain management, dentists, prosthodontists, xerostomia management, smoking and alcohol cessation, tracheostomy and wound management, social workers and case management. Initial management may require surgery, chemotherapy, and radiation therapy in various combinations and sequences. These schedules are based on the extent of the primary and nodal disease as well as the treatment intent, such as definitive, preoperative, or post-operative. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous cell carcinoma of the head and neck. Intensity-modulated radiation therapy for head and neck cancer: emphasis on the selection and delineation of targets. A comparison of intensity-modulated radiation therapy and concomitant boost radiotherapy in the setting of concurrent chemotherapy for locally advanced oropharyngeal carcinoma. Concurrent chemotherapy and intensity-modulated radiotherapy for locoregionally advanced laryngeal and hypopharyngeal cancers. Deintensification candidate subgroups in human papillomavirus-related oropharyngeal cancer according to minimal risk of distant metastasis. Patterns of failure and toxicity after intensity-modulated radiotherapy for head and neck cancer. The potential for sparing of parotids and escalation of biologically effective dose with intensity-modulated radiation treatments of head and neck cancers: a treatment design study. In the management of resected intrahepatic bile duct cancer with positive margins and/or positive regional lymph nodes a. In the management of resected gallbladder cancer with positive margins and/or positive regional lymph nodes a. Because of the underlying cirrhosis, the healthy liver reserve is often decreased. Prior to treatment, an assessment of liver health is necessary and is traditionally quantitated using the Child-Pugh classification system. The Child-Pugh score is based on laboratory and clinical measures and assigns a patient with cirrhosis into compensated (class A) or uncompensated (class B or C) status. Additional measures of liver health include factors of portal hypertension and the presence of varices. Partial hepatectomy, liver transplantation, bridge therapy while awaiting transplantation, downstaging strategies, and locoregional therapies are potentially available. Locoregional therapies include ablation (chemical, thermal, cryo) with criteria regarding tumor number, size, location, and general liver health often dictating the ideal approach. Locoregional therapy may be performed by laparoscopic, percutaneous, or open approach. Arterially directed therapy involves the selective catheter-based infusion of material that causes embolization of tumors using bland, chemotherapy-impregnated, or radioactive products. For each technique, there must be sufficient uninvolved liver such that the technique is capable of respecting the tolerance of normal liver tissue. Systemic therapies include cytotoxic chemotherapy drugs and the multikinase angiogenesis inhibitor sorafenib. These are most commonly utilized in Child-Pugh class A patients, where data demonstrating a benefit in overall survival and better tolerance have been reported. Intrahepatic bile duct cancer (cholangiocarcinoma) the junction of the right and left hepatic ducts serves as the dividing location. Cholangiocarcinomas that occur on the hepatic side of the junction of the right and left hepatic ducts within the hepatic parenchyma are also known as intrahepatic bile duct cancers, or "peripheral cholangiocarcinomas". Those cancers that occur at or near the junction of the right and left hepatic ducts are known as Klatskin tumors and are considered extrahepatic. Early stage cancers in this location are less likely to present with biliary obstruction than their extrahepatic counterparts. Surgical resection has the highest potential for cure, though surgery is often not possible due to local extent of disease or metastases. Highest surgical cure rates are seen if there is only one lesion, vascular invasion is not present, and lymph nodes are not involved. The role of adjuvant radiation therapy after resection is not firmly established, but is considered an option for adjuvant management in the post-resection R1 and R2 situations, and/or when nodes are positive, for definitive management of unresectable tumors, and for palliation. Numerous other methods of locoregional treatment, such as radiofrequency ablation, transarterial chemoembolization and photodynamic therapy are available. When radiation therapy is used, the preservation of normal liver function and respect for constraints of nearby other normal organs must be maintained. Extrahepatic bile duct cancer (cholangiocarcinoma) the junction of the right and left hepatic ducts serves as the dividing location of intra-and extrahepatic bile duct cancers. Those extrahepatic cholangiocarcinomas that arise near the right and left hepatic duct junction are known as hilar or Klatskin tumors.

Syndromes

  • Nutcracker esophagus
  • Avoid brushing your hair too often or too vigorously, since the brushing will carry oil from your scalp to the ends of your hair.
  • Breathing difficulty
  • Potassium test
  • Increased osmotic fragility
  • Tumor
  • Paralysis, weakness, or sensation changes due to loss of nerve function
  • To find out the type of leukemia or lymphoma

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In this area prostate cancer in men buy alfuzosin 10mg overnight delivery, carefully designed pilot control programs would provide extremely valuable data prostate cancer radiation treatment order 10 mg alfuzosin visa. Fungal Infections Fungal infections that affect the skin and adjacent structures are common in all environments prostate cancer 04 purchase alfuzosin 10mg with mastercard. They include infections such as ringworm or dermatophytosis; superficial candidosis and infections caused by lipophilic yeasts and Malassezia species; and some other common causes of foot infection prostate cancer lancet oncology buy cheap alfuzosin 10mg online, such as Scytalidium. The clinical and social impact of fungal infections on individuals varies with local conditions. For instance, tinea pedis is a treatable condition that causes cracking and inflammation with itching between the toes. It is generally viewed as a nuisance that only marginally affects the quality of life; however, under certain conditions its significance is far greater. For example, fungal infections of the web spaces and toenails in diabetics provide a portal of entry for S. Similarly, foot infections originally caused by dermatophytes can develop into more serious disabling infections through secondary Gram-negative bacterial infection among certain occupational groups in the tropics, such as workers in heavy industry, the police, or the armed forces. Whereas in many patients it may simply have nuisance value, in others it has a more serious impact and leads to dysphagia and loss of appetite. Malassezia infections such as pityriasis versicolor are also common in the developing world and often occur in more than 50 percent of the population; however, they are generally asymptomatic but cause patches of depigmentation, and patients seldom seek treatment. Some fungal infections are extremely widely distributed or common in defined endemic areas. Tinea capitis is a common, contagious disease of childhood that can spread extensively in schools. It is caused by dermatophyte fungi of the genera Trichophyton and Microsporum (Elewski 2000). Infections can spread from child to child (anthropophilic infections) or from animals to children (zoophilic infections). Anthropophilic infections tend to be endemic or epidemic, whereas the zoophilic forms occur sporadically. The commonest sources and causes of zoophilic infections are cats and dogs (Microsporum canis), cattle and camels (Trichophyton verrucosum), and rodents (T. The causes of the anthropophilic form of this infection vary in different areas of the world. Although in areas of the developing world this condition is endemic at high levels, in many parts of Africa it is a common condition affecting more than 30 percent of children in primary schools. No evidence indicates that this form has spread to Africa yet, although this possibility exists. However, in a small proportion of individuals, tinea capitis produces a highly inflammatory lesion with suppuration on the scalp along with permanent scarring and local hair loss. The numbers of infected individuals showing this highly symptomatic change are not known with any accuracy, but it is believed to occur in about 5 percent of cases, more with T. This factor poses a dilemma in management, because where the disease is common and endemic, a regular source will always exist for new, severe, inflammatory infections in children. Therefore, addressing this issue by tackling individual cases without addressing the reservoir, albeit illogical, may ultimately be the most practical approach. The diagnosis of tinea capitis is difficult to make clinically in mild cases because the main presenting signs are localized patches of hair loss with fine scaling. With the inflammatory forms, circumscribed patches of hair loss with erythema and pustulation also occur, and the whole area is raised into a boggy mass. The only way to confirm the diagnosis accurately is to take hair samples for culture and microscopy, which is not possible in many areas because they lack laboratory diagnostic facilities. One specific form of tinea capitis, favus, is clinically recognizable and distinct, because the scalp is covered with white plaques called scutula. Inhabitants of endemic areas often recognize favus as a distinct condition that causes chronic illness, and as a result, the uptake of consultation for treatment is higher. The most widely available of these is griseofulvin, which is given to children in doses of 10 to 20 milligrams per kilogram daily for a minimum of six weeks. Noncontrolled studies show that a single dose of 1 gram of griseofulvin given under supervision can eradicate infection in more than 70 percent of individuals, but such regimens have not been adequately assessed under trial conditions to determine their effect on community levels of infection, nor are follow-up data available. Recent years have seen the development of a number of effective, new, oral antifungals, including terbinafine, itraconazole, and fluconazole. Terbinafine is a highly active agent that is effective in the treatment of dermatophyte infections. Unfortunately, at these doses it is less effective for Microsporum infections, although some data suggest that responses are significant if the doses are doubled. This drug is, therefore, difficult to administer in standardized protocols when the cause of infection is uncertain. Itraconazole is also effective, but no suitable pediatric formulation is available because it is marketed in a capsule form that is difficult to administer to young children. Fluconazole is also effective, 714 Disease Control Priorities in Developing Countries Roderick Hay, Sandra E. Bendeck, Suephy Chen, and others although comparative studies of its use are not available. All three drugs are costly, and a community-based program that uses them would be difficult to fund and implement. The effective treatments included topical therapies (benzoic acid, bifonazole, selenium sulfide, ketaconazole shampoo, and miconazole shampoo) as well as systemic agents (griseofulvin, terbinafine, itraconazole, fluconazole, and ketoconazole). The results of topical treatments appear inferior to those of oral therapy, although they have not been directly compared, and some of the topical agents were applied to prevent transmission rather than to treat infection. Attempts at community control of tinea capitis have been devised but have not been monitored adequately. The methods have been based on surveillance through culture and treatment of all infected children. Culture-based diagnosis is difficult to implement regularly in developing countries. The treatment used for community therapy has been griseofulvin in conventional daily or large single doses, but those approaches have not been compared. In addition, control protocols usually advise treating carriers with topically applied agents such as selenium sulfide (which is relatively cheap) or a miconazole shampoo (which is moderately priced). In practice, some "carriers" are really patients with extremely localized and hard-to-detect infections, and such patients will not respond to topical treatment in the long term. A second problem is the absolute reliance on laboratory confirmation of cultures to direct treatment of carriers. Therefore, other strategies need to be evaluated, such as reducing the community load, perhaps by topical therapy or single-dose griseofulvin, to reduce the risk of spread. An alternative would be to continue with the existing practice of treating individual cases while recognizing that this process ignores the community reservoir. In many parts of the developing world, tinea imbricata is an exotic and unusual infection, with isolated foci occurring in remote areas of Brazil, India, Indonesia, Malaysia, Mexico, and the western Pacific. However, in some specific locations, it is common and endemic, reaching prevalence rates of more than 30 percent in some communities in the western Pacific. For example, extrapolating from a school survey in Goodenough Island, Papua New Guinea, Hay and others (1984) estimate that more than 7,000 people out of a population of about 20,000 were infected. The disease presents in the form of widespread scaling, often arranged in concentric rings or with large sheets of desquamation. The infection may develop early in life and persist into old age without the development of effective immunity. Tinea imbricata often affects wide areas of the body, sparing only body folds and scalp skin. In those areas where it is endemic, it can be a significant problem occupying much of the time of health aid post staff. Individual treatments have depended on the antifungals described earlier, including griseofulvin. Terbinafine and itraconazole are highly effective, but their cost has constrained their use. Some patients may be treated with locally derived treatments, such as the sipoma paint used in Papua New Guinea, which contains salicylic acid, brilliant green, and kerosene. The team found studies of the use of griseofulvin, terbinafine, and itraconazole for tinea imbricata. Some studies did mention sipoma paint and Cassia alata, but no studies evaluating their efficacy have been performed.

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At school In private social settings In public social settings When seeking medial care All Strongly 6 prostate cancer diet plan generic 10 mg alfuzosin otc. To the best of your ability prostate 30 ml discount 10 mg alfuzosin free shipping, please estimate the following ages mens health 7 blood tests order 10mg alfuzosin overnight delivery, if they apply to you prostate cancer 411 order 10mg alfuzosin mastercard. How many people know or believe you are transgender/gender non-conforming in each of the following settings? Mark all that On you first Agethe job recognized that you were "different" in terms of your gender. Agethe job first got care On that you Your current age At school 8. To the best social settings please estimate the following ages, if they apply to you. What is your zipsettingsto accept only numerical data with ages as choices, which was not done here so we needed to clean field shouldsocial code? In addition, it may have been better to list current age at the beginning, to increase response rates. To the you firstyour ability, please estimate the following ages, if they apply to you. Age you began to alongside as a transgender/gender outcomes, family acceptance and discrimination. For example, future American Indian or time such issues as or principal tribe) Age you you data to determine how recently respondents transitioned or when they transitioned by decade. Your currentor Pacific Islandertransgender/gender-non-conforming identity Asian recognized your Age you first age Arab or Middle Eastern Age you began to live part time as a transgender/gender non-conforming person. Do you Multiracialto liveto live full-timetransgender/genderdifferent from youperson. Your current recognized that Age you first age want to liveyou were "different" in terms of your gender. Age you first recognized your transgender/gender-non-conforming identity 9. Do you or do you to liveto livetime as a in a gender that is different from you gender at birth? Age to determine We used this answeris your currently live full-timetransitioned, who from my birthand who did not want to . What is youryou want to live full-time in a gender that is different from you gender at birth? We did notIndian or Alaska Native (enrolled or principal tribe) do so. What is your or Pacific Islander Arab Whiteor Middle Eastern Multiracial or mixed race Black or African American Al M N American Indian or Alaska Native (enrolled or principal tribe) Hispanic or Latino Asian or Pacific Islander Arab or Middle Eastern Multiracial or mixed race We intentionally deviated from the Census-style race question here for the purpose of brevity. It is usually simpler for comparative purposes to draw on existing questions in federal surveys, but we continue to believe we made the right decision. Doctorate degree (for example: PhD, EdD) Elementary and/or junior high Some current gross 12th grade 13. How many people$49,999 $50,000 to $59,999 Number $60,000 to $69,999 $70,000 to $79,999 15. If you are currently enrolled, please mark the $200,000 to $250,000 Partnered previous grade or highest degree received. More than and/or junior high Civil union $250,000 Elementary Married Some high school to 12th grade 14. High school Number credit, but less than 1 year We asked respondents only about household income, not individual income. Therefore, we do not know to what extent our respondents Divorced Some college Widowed school degree (such as Technical reported. The income ranges presented in the survey had access to the incomechildren currently rely on yourcosmetology or computer technician) instrument vary slightly from increments they 15. Because I am transgender/gender non-conforming, life in general is: Doctorate degree (for example: PhD, EdD) Civil union Much improved not allow us to say who was above or below the poverty line. Poverty lines are determined this way of asking the question did Married Somewhat improved 13. Separated separately for individuals than $10,000 of various sizes, but our questions did not capture household size nor did the survey ask about the same families Less and Divorced $10,000 to $19,999 income with enoughSomewhat worseus to determine whether a given household was above or below the line. This would have been specificity for Widowed Much worse $20,000 to $29,999 important data. In some ways better, in some ways worse $30,000 to $39,999 Important$40,000 to $49,999 "Because you are transgender/gender non-conforming, has one or two of these things happened to Note: When we say: you," we do not mean$59,999 gender identity or expression is causing bad or abusive things to happen. We are trying to find out if $50,000 to that your slightly compromised our ability to detect the effect of discrimination on income. For example, if Asking about household income likely people are treating you differently because you are transgender or gender non-conforming. Number these data were unusable because we did not clarify whether the person should include his or herself in the answer (thus, an answer of Number 1 might mean they live alone or it might mean they live with one other person). Technical degree (for example: PhD, EdD) Doctorate $89,999 $80,000 toschool degree (such as cosmetology or computer technician) One or more years $90,000 to $99,999of college, no degree Associate degree (for 13. Doctorate $39,999 $30,000 todegree (for example: PhD, EdD) Elementary and/or junior high $40,000 to school to household? Simpler, standard questions relating to parental status, Civil than $79,999 relying on income could referdegree (for example: PhD, EdD) Doctorate $80,000 to $89,999 Married number of children manychild-rearingyour household? See note on Important$20,000 to $250,000 "Because you are transgender/gender non-conforming, has one or two of these things happened to QuestionNote: When we say: 20 than $29,999 More for how Number we determined parental status. How istreating you differently because you are transgender or gender non-conforming. Because I am transgender/gender non-conforming, life in general is: $70,000 to $79,999 15. Civil union Much improved $80,000 to $89,999 Number Married Somewhat $99,999 $90,000 to improved Separated the same $100,000 to $149,999 16. Divorced worse Somewhat $150,000 to $ 199,999 Singleworse Widowed Much $200,000 to $250,000 Partnered In some ways better, More than $250,000 in some ways worse this question met our analytic needs because we grouped together all ofnon-conforming, has one or two of these things happened to to ImportantCivil union we say: "Because you are transgender/gender those in a relationship. How many mean live your gender identity or expression is causing bad or abusive things to happen. How manyam transgender/gender non-conforming, life in general is: Much improved Number ImportantSomewhat improved "Because you are transgender/gender non-conforming, has one or two of these things happened to Note: When we say: you," we do not mean that your gender identity or expression is causing bad or abusive things to happen. Somewhat worse Single Much worse Partnered In I am ways better, generally to be avoided. We used the phrase Much worse In some a respondent being targeted better, discrimination reported andwayswe say:in some ways worse based on gender identity or expression. Because I am transgender/gender non-conforming, life in general is: Much improved Somewhat improved the same Somewhat worse Much worse In some ways better, in some ways worse 18. Because I am transgender/gender non-conforming, my housing situation is: Much improved Somewhat improved the same Somewhat worse 18. Because I am transgender/gender non-conforming, my housing situation is: Much worse improved In some ways better, in some ways worse Somewhat improved the same 19. If you are or were employed, how including a not applicable optiongender non-conforming changed your employment this question could have beenworse Somewhat improved by has the fact that you are transgender/ for those who have not come out as transgender/gender situation? Much improved In some ways better, in some ways worse Somewhat improved Stayed the employed, how has the fact that you are transgender/ gender non-conforming changed your employment 19. Somewhat worse Much worse improved In some ways better, in some ways worse Somewhat improved Not applicable. Much worse Much improved In some ways better, in some ways worse Somewhat improved never employed Not applicable. I was Stayed the same Somewhat worse the not applicable answer could have been improved by also noting that the question may not apply to people who have never come 20. Much worse Homeless In some ways better, in some ways worse Living in a shelter not a parent. Because you are transgender/gender non-conforming, have you experienced any of the following housing situations? Please mark "Not applicable" if you were never in a position to experience such a housing situation. For example, if you have always owned your homemoved into a less expensive home/apartment. Yes Yes Given the high rates of youth homelessness due to parental rejection, it would have been helpful if we had added options like "I was kicked out of my family home before the age of 18" and "I was kicked out of my family home over the age of 18.

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After the consultation man healthcom 2014 report discount alfuzosin 10 mg amex, my colleague would like to talk with you about your experience here today prostate biopsy results order alfuzosin 10mg fast delivery. We are conducting a study of health facilities in Tanzania in order to improve the services this facility offers and would like to ask you some questions about your experiences here today prostate mri radiology generic alfuzosin 10mg overnight delivery. Information from this interview may be provided to researchers for analyses prostate cancer 79 year old effective 10mg alfuzosin, but neither your name nor the date of services will be on any shared information, so your identity will remain completely confidential. During this visit (or previous visits) did a provider give you iron pills, folic acid or iron with folic acid (FeFo), or give you a prescription for them? During this visit (or previous visits) has a provider explained to you how to take the iron pills or FeFo? During this visit (or a previous visit) did a provider advice you to use mosquito net that has been treated with an insecticide? During this visit (or a previous visit) did a provider offer you a mosquito net that has been treated with an insecticide free of charge? During this visit (or previous visits) has a provider talked to you about nutrition or what is good for you to be eating during your pregnancy? This may include planning in case of emergency, things you should bring to a facility, or things you should prepare at home for this delivery. Please tell me some of the things you know of that you should have in preparation for the delivery. For how many months did the provider recommend that you exclusively breastfeed, that is, that you do not give your baby any fluids or food in addition to breast milk? During this visit (or previous visits) did a provider talk with you about using family planning after the birth of your baby? I would like to have your honest opinion about the things that we will talk about. Were you charged, or did you pay fees for any services your received or were provided today? I would like to have your honest responses as this information will help to improve services in general. And although information from this observation may be provided to researchers for analyses, neither your name nor the date of services will be provided in any shared data, so your identity and any information about you will remain completely confidential. Please know that whether you decide to allow me to observe your visit is completely voluntary and that whether you agree to participate or not will not affect the services you receive. We are conducting a study of health facilities, with the goal of finding ways to improve the delivery of services. You may refuse to answer any question, and you may stop the interview at any time. Have you used a family planning method or taken any steps to prevent pregnancy at any time during the past 6 months? What was the outcome of this visit-did you decide to continue (restart) the same method or to switch methods? Had you thought about what family planning method you wanted to use before you came here today? As I mention each one, please tell me whether any of these were problems for you today, and if so, whether they were major or minor problems for you. I would like to observe your consultation with this client in order to understand how services for sick children are provided in this facility. I would like to be present while you are receiving services today in order to understand how sick child services are provided in this facility. And although information from this observation may be provided to researchers for analyses, neither your name nor the date of service will be provided in any shared data, so your identity and any information about you will remain completely confidential. Please know that whether you decide to allow this interview or not is completely voluntary and will not affect services you receive during any future visit. Regarding this referral, please tell me: 01 Were you given any paper or record to take with you for the referral? Now I am going to ask about some common problems clients have at health facilities. The following is a description, separated by agency, of evidence work as a whole, and efforts to advance the use of evidence in decision-making. Department of State Officials/Offices Responsible for Evaluation Functions (a) Senior Evaluation Officials/Lead Evaluation Offices Within the U. The F Director is a political appointee and both individuals promote a culture of data analytics and evidence to inform decision-making. Both entities include leadership and staff which guide evaluation policy and support its implementation throughout the Department. Foreign Assistance Resources focusing on the implementation of policy, capacity building, and oversight. Staff with these specialties are complemented with 42 Bureau Evaluation Coordinators, who are personnel with training in the management of evaluations that carry out the functions listed above. Agency Strategy to Advance the Use of Evidence in Decision-Making (a) Current Efforts and Future Plans the Department of State continues to strengthen program, project, and process management guidelines to help align activities to strategy and meet desired goals. Using the Managing for Results Framework (MfR), State continues to improve processes to build evidence, increase the quality of evaluations, and to integrate planning, budgeting, managing, and learning processes to inform and support programmatic, budget, and policy decisions. To integrate the MfR more fully within bureaus and missions, State created a website to provide information, tools, and templates pertaining to work in all four quadrants of the 1 cycle: planning, budgeting, managing, and learning. Recent accomplishments have included: Developing and promoting a Program Design and Performance Management toolkit to assist bureaus in implementing the policy. State developed an online evaluation toolkit and resources for bureaus to use in concert with the Program Design and Performance Management Toolkit. Developing and piloting a four-day training course on Strategic Planning and Performance Management. Bureaus and Missions have updated their strategic plans to align with the Joint Strategic Plan. All of these improvements help inform and empower decision-makers when making programmatic and budgetary decisions. There has been an increase in agencies reporting financial transaction data to ForeignAssistance. As of 2016, only 10 agencies had been reporting, which increased to 18 in 2017 and 19 in 2018. By expanding the use of existing Department data assets and focusing on internal capacity, the Department will enable staff to provide better evidence-based solutions to the global challenges they confront. With these new courses, staff all over the Department will be able to better integrate data and visualizations into their analyses and enable leaders to more regularly have access to data-informed decision-making materials. The policy is supported by internal guidance, an internal online Evaluation Toolkit, and the Program Design and Performance Management Toolkit, which provides step-by step instruction, examples, and templates for setting program-level goals, creating logic models, designing performance indicators, developing monitoring and evaluation plans, and using data for learning. In addition to the Toolkit, State offers technical assistance and classroom training to support implementation. For example, an evaluation on security sector assistance is looking at the extent to which U. Another evaluation explores programs to counter violent extremism by looking at two projects in neighboring countries experiencing similar issues that use different approaches to achieve similar outcomes. The evaluation is expected to provide additional insight into an often asked question about the effectiveness of face-to-face training versus other methods of delivery. It continues to strengthen staff skills through training and to make more information available online. Currently, significant barriers include: Ensuring sufficient Department-wide resources dedicated to evaluation covering both staffing and funding. Currently bureaus are doubling up on job duties and carefully analyzing where best to focus resources. Each evaluation of a program or project can be useful for improving effectiveness, efficiency and future planning and design. This takes time as well as the capacity to store, share and use information about evaluation results across sectors, regions or functions that managers can use to track and leverage. The Department is working toward curating this data as well as improving its capacity to interpret the data. Agencies outside the Department need to fulfill their reporting mandates to ForeignAssistance.

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