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Ernest L. Mazzaferri, Jr., MD, FACC

  • Associate Medical Director
  • Richard M. Ross Heart Hospital
  • Assistant Professor, Interventional Cardiology
  • The Ohio State University

In relation to the gene-for-gene hypothesis blood pressure chart india buy cheap lozol 1.5 mg on line, much resistance to insects requires quantification to assess it arteria festival 2013 buy lozol 2.5 mg visa. It is noticeable that the biotype problem has arisen most frequently with aphids hypertension icd 9 code order 2.5 mg lozol fast delivery, among the fastest-breeding pests arteria dawson generic lozol 1.5 mg with amex. The concept of resistance-breaking biotypes of plant diseases is related to the gene-for-gene hypothesis (Flor, 1942). This hypothesis states that major genes for resistance in a plant arc matched by corresponding genes in the disease for overcoming that resistance. Where resistance to a pest or disease is mediated by a single gene or a few genes (monogenic or oligogenic resistance), it becomes clear-cut and race-specific (for example Table 5. Unfortunately, most plant breeding for yield and quality is carried out under chemical protection. As selections are then made without reference to the effects of pests and diseases, horizontal resistance becomes eroded in most plant breeding programs. Clearly vertical resistance is much more likely to suffer from biotype problems than horizontal resistance. However, monogenic or oligogenic resistance is very much easier to transfer into adapted varieties, especially by transgenic methods. Figures in body of table represent level of plant susceptibility of each combination as a percentage of maximum (from van Emden, H. A solution might be to breed high acceptability into varieties antibiotic to the vector. Ekpo and Thottappilly (191-14) shmved experimentally (in cages) that cowpea mosaic virus vas spread more rapidly in two covvpea varieties resistant to Aphis cmccivom than in a susceptible variety. Insecticides and biological control have both been identlfied as having the potential for potentiation with such partial plant resistance (van Emden. Even small levels of plant resistance seem to allow the same kill as on a susceptible variety to be achieved with dose reductions of about one-third. Biological comrol and plant resistance Reference was made earlier to deleterious effects on natural enemies of feeding on prey on resistant plants. Such potentiations can be defined as pest population reductions on partially resistant plant varieties greater than expected from the equivalent reduction on a susceptible variety. Van Emden (1990a) summarizes the literature reporting such potentiaticm of biological control on partially resistant varieties. However, the phenomenon also carries the danger that plant resistance based on allelochemicals may well deter parasitoids. With smaller prey, the impact of predation also rises with density to higher prey densities than with larger prey. Kennedy and Johnson (199 I) have pointed out that any such potentiation of biological control by plant resistance will affect unadapted genotypes of the pest more than adapted ones. This is bound to lead to an acceleration in the spread of genes adapted to the plant resistance. It can equally be argued that positive synergism between partial plant resistance and insecticides will accelerate tolerance developing to both insecticide and plant resistance. The three-way interaction Natural enemies may or may not be killed by lower concentrations of a toxin than those which kill their prey (p. These considemtions combine to afford a remarkable opportunity for increasing the natural enemy:pest ratio on resistant varieties whenever insecticides arc used (compare Figures 5. The curve for pest mortality shifts to lower concentrations on resistant varieties (unless the resistance is based on allelochemicals, see earlier). However, a similar shift for the natural enemy only occurs to the extent of any weight reduction resulting from feeding on smaller prey. We could seek resistant varieties on which pests are more easily killed with insecticide. More commonly, we develop resistant varieties on which pests are tolerant to insecticide and v. It would only interest plant breeders as a bonus property of varieties being developed for quite other desirable characters. Ecdysone Ecdysone (molting hormone) regulates the destruction of the old insect cuticle and the development and hardening of the new. Although ecdysones interfere lethally with these processes in experiments, there proved to be commercial problems in exploiting them. They are of low toxicity to vertebrates and break down into harmless substances in the environment. Typical effects of these compounds as pest control agents are usually seen at larval to pupal metamorphosis, where lethal deformations and even intergrades between larva and pupa appear. Roth have been used particularly in public health and stored food products (Menn, Raina and Edwards, 1989). With the potent advantages of antagonists, much research has been devoted to them over what is now many years. Although the formation of the new skin proceeds normally, cuticle inhibitors disrupt the actual molting process itself. Affected insects either die totally within the old ctJticle or only partly emerge from it. Several agrochemical companies are now involved in R & D and marketing of cuticle inhibitors. It has, where appropriate, emphasized that the combination of two or more measures may lead to more than additive results. Any use of insecticides is firmly related to scouting and thus to economic thresholds, which are known for all the regular pests. When thresholds are exceeded, farmers have advice available on what arc at least partially selective insecticides so that natural enemies are conserved as far as possible. Although any item in the menu that contributes to fewer pesticide applications and the use of better compounds will contribute to increased biological control, the menu <1lso includes biological control specifically. Many plant characteristics have been identified as leading to pest resistance in cotton, and a number have been incorporated into commercially acceptable varieties. Most arc designed to capitalize on the possibilities early harvest gives for minimizing bollworm damage. Such earliness of maturity may be inducible by early termination of irrigation and the spraying of leaf desiccants to synchronize early boll opening. Early harvesting needs to be coupled with early destruction of the stalks remaining in the field after harvest. Other cultural measures available are insecticide-treated trap crops against boll weevil, and the possibility of holding Lyyus bugs on any adjacent lucerne (and thus away from cotton) by strip harvesting rather than total combining of the former. Such a menu system can be offered to farmers because of the resources that have been invested in research on cotton insect pests and their control at many research stations and universities over many years, including before Silent Spriny. The second feature of such a system is that it represents a synthesis of target-specific controls: it is perhaps characteristic of a menu system that exploitation of useful synergism between components has to be foregone. Thirdly, the system is very crop-specific; the same menu cannot be applied in any crop other than cotton. Again, it is crop-specific and the outcome of putting together the results of many years of research. It is interesting that the growers themselves have often requested this menu from the scientists. Such requests stem from a fear ofinsecticide resistance in the pests as the number of insecticides registered for use in orchards has shrunk dramatically. The computer programs are based on systems analysis, life-table studies and mathematical modeling. Pivl the immediate reaction of many scientists is that meaningful modeling of a single pest population. It has sometimes been possible to use just a few key parameters to predict pesticide outbreaks or the need for pesticide treatment. Some very usable computer models of crop growth and the effect thereof on pest populations have already been achieved for several crops. These models have already proved themselves in their ability to predict whether and when economic thresholds will be reached in the field. The model simulates the assimilated flux of the whole tree, and also the phenology of growth of the leaves, shoots. The protocol is based on the results of lleld trials rather than on foreknowledge and collection of basic biological and ecological data (van Emden, 1989). If each treatment is then tested with and without release of a biological control agent and with and without a change in cultural measures (e.

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It was a strange blood pressure medication exercise generic lozol 1.5 mg with visa, silent place prehypertension exercise 2.5 mg lozol fast delivery, but there was water in a creek and the hunting was good blood pressure natural discount lozol 1.5 mg with mastercard. Often she thought they were footsteps pulse pressure explained buy 2.5 mg lozol, but when she looked outside, no one was there. They and the sister stayed awake all night, wondering what could have happened to the other. In those early days the Indians had no sacred ceremonies or prayers to guide them, so it was hard for the maiden and her two brothers to watch through the night in that ghostly place. Again the brothers went out in the morning, and only a single one returned at night. But they had to eat, and so in the morning her last and youngest brother, whom she loved best of all, went out to hunt. She drank some water and felt a stirring inside her, as if the rock were telling her not to worry. Day after day he grew, ten times faster than ordinary infants, and with a more perfect body. One day when he was playing outside the tipi, he made a bow and arrows, all on his own. His hair became long, and as he matured his mother became afraid that she would lose him as she had lost her brothers. Very soon he was big enough to go hunting, and when she saw this, his mother wept more than ever. She watched him pass and, calling him over, invited him to eat and, stay the night. Stone Boy went into the tipi, though he was uneasy in his mind, and a little timid. He looked around and saw nve big bundles, propped up on end, leaning against the tipi wall. Later she nxed a dirty old buffalo robe for him to sleep on, but he sensed danger and felt wide awake. As he did, he felt something sticking up under her buckskin robe, something sharp like a knife or a needle or the point of a spear. He jumped and jumped until he was exhausted and the hag was lying dead with a broken back. Then Iyan Hokshi walked over to the big bundles, which were wrapped in animal hides and lashed together with rawhide thongs. He unwrapped them and found nve men, dead and dried like jerked meat, hardly human-looking. He set the rocks right in the Bames, picked up the old woman, and threw her in to burn up. After the rocks glowed red-hot, Stone Boy found a deer antler and used it to carry them one by one into the little hut he had made. Iyan Hokshi dosed the entrance of his little lodge with a Hap of buffalo robe, so that no air could escape or enter. Pouring water from the bag over them, he thanked the rocks, saying, "You brought me here. As he poured, the little lodge filled with steam so that he could see nothing but the white mist in the darkness. And when he poured the fourth time, those dead, dried-up things also began to sing and talk. The bonfire and the moonlight both shone into the little sweat lodge, and by their light he saw five good looking young men sitting inside. This little lodge, these rocks, the water, the fire-these are sacred, these we will use from now on as we have done here for the first time: for purification, for life, for wichosani, for health. Henry Crow Dog is a full-blooded Sioux elder with a majestic face, craggy as the Black Hills themselves. He is the grandson of the famous Crow Dog, a chief, warrior, and leader of ti1e Ghost Dancers. The first Crow Dog once voluntarily drove 150 miles to his own hanging for killing his rival, Chief Spotted Tail, only to be freed on orders of the Supreme Court, which ruled that federal law had no jurisdiction on an Indian reservation. Thinking that the infant would not live, the father wrapped it carefully and placed it in a hollow tree outside the lodge. After a time he heard crying from the hollow tree, for the baby too was lonely, and hungry as well. When he discovered his little brother, the boy made him some soup from deer intestines, which the baby drank with relish. The older brother made a little coat out of fawn skin; when he put it on, the baby looked like a chipmunk scampering around. When he came home, the father noticed that the deer intestines were gone and asked the boy what he had done with them. Then he walked beyond the tree and crouched down so that he looked like an old stump. Suddenly the stump turned into a man, who caught the little one,in his arms and ran to the lodge. Then he laid about him with the club, and everything he hit at was either crushed or killed. He fixed himself a pile of red-hot stones and, hurling them at the frogs, killed everyone. Raising his club, the little boy, the powerful one, struck Thunder and crushed his head, so that he fell dead to the ground. The powerful boy struck her on the head as he had done with her husband, and she fell dead. They bring rain and do us good, but now they will destroy us to revenge their children. So the father took the skin for a tobacco pouch, but he said, "You must never go north to the country where Stone Coat lives. Thinking that the master must be close by, the little boy jumped into the heart of a chestnut tree to hide. The little boy cut off pieces of meat, cleaned them as fast as he could, and put them into his mouth. He kept running in and out, in and out, until all the flesh of his bear had disappeared. Then he played with three more, and when they lost he put them with the first three, and so on-until he decided that the number was large enough. As the boy approached, a number of people who had lost their bets were waiting to be killed. Hope came to them all, for they sensed that this child had great orenda-power, or medicine. When the big-headed man threw the dice, the bay caused some to remain in the dish and others to go high, so that the dice came to rest with different designs showing. But when the boy threw, the dice turned into wood cocks, flew high, and came down as dice of the same design. The two played until the boy won back all the people and the gambler lost his own big head, for the boy instantly cut it off. There the ilolf and the Bear clans were playing against the Eagle, the Turtle, and the Beaver clans. While archeological evidence confirms that the Iroquois have inhabited upstate New York and northeastern Pennsylvania continuously for literally thousands of years, their cultural myths still include tales of a great migration into the beautiful country of the East from a previous homeland. This may refer to the arrival of other related tribes from the south and west who joined the core population during different periods. Now Glooscap had never married and was ignorant of how children are managed, but with perfect confidence he smiled at the baby and asked it to come to him. Unaccustomed to such treatment, Glooscap lashed himself into a rage and in terrible and threatening accents ordered Wasis to come to him at once. He sang the songs which raise the dead, and those which send the devil scurrying to the nethermost depths. At last Glooscap rushed from the hut in despair, while Wasis, sitting on the floor, cried, "Goo, goo! North, as it is spoken of at the beginning of both tales, is a nostalgic reference to the Cheyenne hunting grounds in north-central America, from which they were driven by invading tribes, probably the Ojibway. In order to win, a player had to throw his stick through the hoop while it was still moving. A large audience had already gathered when a young man came from the south side of the camp circle to join them.

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A dislocated prosthesis is evidenced by any of the following six indicators: how quickly should blood pressure medication work order 1.5mg lozol with mastercard, and pulse pressure 68 discount lozol 2.5 mg on line. The nurse advises the patient that an acute infection may occur within how many months of surgery with delayed infections occurring up to how many months The intervertebral disks that are subject to the greatest mechanical stress and greatest degenerative changes are hypertension kidney infection discount 2.5mg lozol otc. Back pain is classified as "chronic" when the pain lasts without improvement for longer than prehypertension statistics discount lozol 2.5mg with amex. When lifting objects, patients with low back pain should be encouraged to maximize the use of the following muscles. The nurse should encourage a patient with low back pain to do all of the following except. The average 75-year-old woman with osteoporosis has lost how much of her cortical bone The estimated intake of calcium to prevent bone loss for a postmenopausal woman is mg/day. Appropriate nursing actions when caring for a patient with a primary malignant bone tumor would include all of the following except. List four nursing diagnoses for a patient undergoing foot surgery:, and. Three significant characteristics of osteoporosis are:, and. Primary osteoporosis in women usually begins between the ages of:. Explain the effects of the following on the development of age-related osteoporosis. Describe "impingement syndrome" and the measures necessary to promote shoulder healing. Discuss the etiology and medical treatment for the nine common foot problems listed in the chapter; for example, plantar fascitis, corn, and hammer toe. Describe the risk factors (modifiable and nonmodifiable) that are associated with osteoporosis. Describe the clinical manifestations and medical and nursing interventions for septic arthritis. What two reasons could the nurse use to explain why women develop osteoporosis more frequently than men: and. The nurse advises Emily that about of Caucasian women older than 50 years of age have some degree of osteoporosis. The nurse advises Emily that the development of osteoporosis is significantly dependent on. The nurse knows that Emily has probably already exhibited demineralization. After arthroscopic surgery for a rotator cuff tear, a patient can usually resume full activity in. A patient who has a meniscectomy by arthroscopic surgery needs to know that normal athletic activities can usually be resumed after. An open fracture with extensive soft tissue damage is classified as a what grade fracture The femur fracture that commonly leads to avascular necrosis or nonunion because of an abundant supply of blood vessels in the area is a fracture of the. Patients who experience a fracture of the humeral neck are advised that healing will take an average of weeks, with restricted vigorous activity for an additional weeks. An immediate nursing concern for a patient who has suffered a femoral shaft fracture is assessment for. The longest immobilization time necessary for fracture union occurs with a fracture of the. A nurse can foster a positive self-image in a patient who has had an amputation by all of the following except. Crepitus, a grating sensation felt when the hands are placed over an extremity, is caused by:. Patients with open fractures risk three major complications:, and. List three early and delayed complications of fractures: Early:, and. Treatment of early shock in fractures consists of five activities:, and. List three early and serious complications associated with bed rest and reduced skeletal muscle contractions for a patient with an open fracture:, and. The most common fracture of the distal radius is:. The most common complication of hip fractures in the elderly is:. Common pulmonary complications, after hip fracture, for the elderly include: and. Three range-of-motion activities are avoided for a patient with a lower extremity amputation:, and. The residual limb should never be placed on a pillow to avoid:. A dislocation: lack of contact between the articular surfaces of bones:: : partial dislocation of associated joint structures. Closed reduction: the alignment of bone fragments into opposition:: open reduction:. Delayed union: delayed healing due to infection or poor nutrition:: nonunion:. Intracapsular fracture: neck of the femur:: extracapsular fracture:. Compare the nursing assessment and medical management for first-, second-, and third-degree strains and sprains. Distinguish between open and closed reduction as a management technique for fractures. Explain the clinical manifestations and underlying pathophysiology of fat embolism. Explain the etiology, clinical manifestations, and medical management for compartment syndrome. Distinguish between the clinical manifestations and medical and nursing management of intracapsular and extracapsular fractures. The foot is firmly planted and the knee is struck laterally, as in basketball or soccer. The patient will immediately experience, and the inability to walk without assistance. Patients who report that their knees "give way" or "lock" after twisting or repetitive squatting are most likely experiencing a. Normal activities can be resumed in (weeks/months). He is scheduled to have an above-the-knee amputation of his left leg because of peripheral vascular disease. Preoperatively, the nurse knows that the circulatory status of the affected limb should be evaluated by assessing for. Preoperatively, the nurse needs to assist William in exercising the muscles needed for crutch walking. Preprosthetic nursing care should attempt to avoid any problem that can delay prosthetic fitting, such as. A gram-positive organism that is less virulent than a gram-negative organism is. Chickenpox and Herpes Zoster (also known as Shingles) are both caused by the same viral agent. A gram-negative bacillus, linked to contaminated eggs or chicken, that causes diarrhea is. A common bacterial cause of diarrhea that has been linked to the ingestion of undercooked beef is.

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Other factors that can affect vital capacity include: aerobic conditioning of the subject blood pressure medication over prescribed buy cheap lozol 1.5mg on-line, chronic obstructive pulmonary diseases blood pressure chart xls generic lozol 2.5mg with mastercard, smoking arteria epigastrica inferior purchase lozol 2.5 mg amex, etc ulterior motive meaning buy lozol 2.5mg low price. Activity 6: Visualizing Respiratory Variations Using the Physiograph-Pneumograph Apparatus (pp. Stretch receptors in the lungs are sensitive to extreme inflation and extreme deflation of the lungs. Impulses to the medulla oblongata initiate expiration or inspiration, respectively. The hyperventilation tracing should be similar in height and depth to the vital capacity tracing, but with an increased rate. Increased intrathoracic pressure reduces blood flow back to the heart, decreasing cardiac output. Activity 7: Demonstrating the Reaction Between Carbon Dioxide (in Exhaled Air) and Water (p. Carbon dioxide in the exhaled air combines with water to form carbonic acid, lowering the pH of the solution. The contrast between the pH change with water alone and the pH change with buffer should be clear. For each of the following cases, check the column appropriate to your observations on the operation of the model lung. Diaphragm pushed up Change In internal volume of the bell jar (thoracic cage) In internal pressure Increased Decreased Diaphragm pulled down Increased In the size of the balloons (lungs) In direction of air flow Into lungs Out of lungs Into lungs Out of lungs 2. Gases move in the direction that tends to equalize pressure inside and outside the "container. Activation of the diaphragm and the external intercostal muscles begins the inspiratory process. What effect does contraction of these muscles have on thoracic volume, and how is this accomplished The diaphragm moves inferiorly, increasing the superior/inferior dimension; the ribs swing up and out, increasing the lateral and anterior/posterior dimensions. What was the approximate increase in diameter of chest circumference during a quiet inspiration What temporary physiological advantage is created by the substantial increase in chest circumference during forced inspiration Increases the thoracic volume more; therefore, creates a greater negative internal pressure, causing the gases to rush in quickly. The presence of a partial vacuum between the pleural membranes is integral to normal breathing movements. What would happen if an opening were made into the chest cavity, as with a puncture wound Destroys the partial vacuum in the pleural space and the lung on the affected side collapses. Write the respiratory volume term and the normal value that is described by the following statements. Would your vital capacity measurement differ if you performed the test while standing When lying down or sitting, the abdominal organs press against the diaphragm, making it more difficult for the di- aphragm to move inferiorly. Chronic bronchitis the volume of air that can be inhaled due to excessive mucus production; emphysema the amount of air that can be exhaled (check-valve effect). Initial testing (student data) breaths/min Record observations of how the initial pneumograph recording was modified during the various testing procedures described below. Indicate the respiratory rate, and include comments on the relative depth of the respiratory peaks observed. Test performed Talking Yawning Laughing Standing Concentrating Swallowing water Coughing Lying down Running in place Observations Respiratory rate becomes irregular during talking. Respiratory rate is regular unless punctuated by intervals of apnea in individuals who hold their breath when concentrating. Respiration rate becomes irregular and marked by depth of expirations during coughing. Impulses are transmitted to the medulla oblongata, which then initiates inspiration or expiration (respectively). Observations for rebreathing air: (student data) Why does rebreathing air produce an increased respiratory rate What was the effect of running in place (exercise) on the duration of breath holding Record student data from the test illustrating the effect of respiration on circulation. Radial pulse before beginning test: Relative pulse force before beginning test: Condition of neck and facial veins after testing: Explain these data. Forced expiration increases intrathoracic pressure, reducing blood flow back to the heart, resulting in dilation of the neck and facial veins. Decreased cardiac output results in increased cardiac rate (seen here as increased pulse rate). Do the following factors generally increase (indicate with I) or decrease (indicate with D) the respiratory rate and depth Where are sensory receptors sensitive to changes in O2 levels in the blood located Aortic bodies in the aortic arch and carotid bodies at the bifurcation of the common carotid artery 24. Which, if any, of the measurable respiratory volumes would likely be exaggerated in a person who is cardiovascularly fit, such as a runner or a swimmer Which, if any, of the measurable respiratory volumes would likely be exaggerated in a person who has smoked a lot for over twenty years How successful was the laboratory buffer (pH 7) in resisting changes in pH when the acid was added Since it is a weak base, it does not function under physiologic or alkaline conditions. What role does exhalation of carbon dioxide play in maintaining relatively constant blood pH Set out the dissectible torso model and anatomical charts of the human digestive system. Set out models of a villus and the liver, if available; a jaw model; and/or a human skull. Set out slides of liver, mixed salivary glands, pancreas; longitudinal sections of the gastroesophageal junction and a tooth; cross sections of the stomach, duodenum, and ileum; lens paper and lens cleaning solution. Answers to Activity Questions Activity 2: Studying the Histological Structure of Selected Digestive System Organs (p. Gastroesophageal Junction the esophagus is lined with stratified squamous epithelium, while the stomach is lined with simple columnar epithelium. Subdivisions of the layer (if applicable) 1) epithelium; 2) lamina propria; 3) muscularis mucosa (not applicable) 1) circular layer 2) longitudinal layer (not applicable) Wall layer mucosa submucosa muscularis externa serosa or adventitia Major functions absorption secretion vascular supply for mucosa; protection churning; mixing; propulsion of food along the tract protection and anchoring for adventitia; reduction of friction for abdominal organs by serosa Organs of the Alimentary Canal 2. Changes from stratified squamous (esophagus) to simple columnar (stomach) How do the epithelia of these two organs relate to their specific functions The esophagus is subjected to constant abrasion (stratified squamous is well adapted for this). The stomach has secretory (and some absorptive) functions and is better protected from acid. The large intestine includes the colon, but also includes the cecum, vermiform appendix, rectum, and anal canal. You have studied the histological structure of a number of organs in this laboratory. Correctly label all structures provided with leader lines in the diagram of a molar below.

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By using the statistical weights blood pressure medication that starts with an l lozol 1.5 mg for sale, nationally representative estimates of emergency department-treated injuries and illnesses are made and can be characterized by demographics heart attack move me stranger 2.5mg lozol mastercard, nature of injury/illness pulse pressure nhs discount lozol 2.5mg with mastercard, and injury event characteristics pulse pressure 57 order lozol 1.5mg amex. Additionally, occupational fatalities, military injuries/illnesses, revisits to the emergency department, common illnesses (e. Notifiable disease surveillance is conducted by public health practitioners at local, State, and national levels to support disease prevention and control activities. Notifiable disease reports are received from health departments in the 50 States, 5 territories, New York City, and the District of Columbia. Policies for reporting disease cases may vary by disease or reporting jurisdiction, depending on case status classification. Reporting is currently mandated by law or regulation only at the local or State level. Thus the list of diseases that are considered notifiable varies slightly among the States. The degree of completeness of reporting is influenced by the diagnostic facilities available; the control measures in effect; public awareness of a disease; and the interests, resources, and priorities of State and local officials responsible for disease control and public health surveillance. Factors such as changes in case definition for public health surveillance, introduction of new diagnostic tests, or discovery of new disease entities can cause changes in disease reporting that are independent of the true incidence of disease. Additional information includes age, race, sex, and State and county of residence at the time of death. The All 50 States query is designed to generate a variety of summary statistics in the form of tables, charts, and maps. Examples of the types of statistics that this application generates are counts of deaths, crude and age-adjusted mortality rates, and years of potential life lost by year, age group, race, sex, underlying cause, contributing cause, or any mention of death at the national, State, and county levels since 1968. Data from additional sources, such as population statistics, comparative standard population, and lifetable values are incorporated into the system. Hospitals participating in this system benefit by receiving technical support and standardized methodologies (including software) for conducting occupational health surveillance activities. The system provides statistics for the surveillance of occupational respiratory diseases in an easily accessible, user-friendly format. Usual occupation and industry of each decedent have been available for several States since 1985. Examples of the types of statistics this system generates are counts of deaths, crude and age-adjusted rates, and years of potential life lost by year, age group, race, sex, and usual occupation or industry at the national, State, and county levels. Data from additional sources, such as population statistics, comparative standard population, and life table values are incorporated into the system. Data elements include coded characteristics such as age, gender, race, occupation, and cause of death. In addition, narrative text for industry, occupation, causes of death, and injury characteristics are entered and maintained for focused research studies. The employment data used for rate calculations are based on the number of workers rather than hours of work (or full-time equivalents). Rates were not calculated for cells with fewer than three cases because of the instability of rates based on small numbers. Frequencies and rates are presented only for the civilian workforce because denominator data are not easily obtainable for military personnel. The goal was to develop models for State-based disease or injury condition-specific surveillance and enhance the capability of the participating States to direct appropriate and effective intervention and prevention efforts. Excluded from the survey are the self-employed, farmers with fewer than 11 employees, private households, Federal government agencies, and employees in State and local government agencies. Survey estimates of occupational injuries and illnesses are based on a statistically designed probability sample rather than a census of the entire working population. Data from this study are used to track, analyze, and report information pertaining to tuberculin skin testing surveillance in health care workers. Each employer completes a single report form, which is used for both national and State estimates of occupational injuries and illnesses. This procedure eliminates duplicate reporting by respondents and, together with the use of identical survey techniques at the national and State levels, insures maximum comparability of estimates. An occupational injury is any injury that results from a work-related event or from a single instantaneous exposure in the work environment. An occupational illness is any abnormal condition or disorder (other than one resulting from an occupational injury) caused by exposure to factors associated with employment. It includes acute and chronic illnesses or diseases that may be caused by inhalation, absorption, ingestion, or direct contact. Lost workday cases involve days away from work, days of restricted activity, or both. In addition to publishing injury and illness counts, rates, and characteristics, the Bureau estimates injury and illness severity using information provided by employers about the number of days away from work needed to recuperate from each disabling condition. If, as a result of injury or illness, the employee did not return to work by the end of the survey year, then the employer reports an approxi- mate return date, which, in conjunction with the date of injury or illness, yields an estimate of days away from work for that case. Half the cases involved more days and half involved fewer days than a specified median. Injuries were defined as any condition that resulted in one-half day or more of restricted activity or required professional medical treatment. An agricultural work-related injury was defined as an injury meeting this definition that occurred while performing work (either on the farm or off the farm) associated with the farm business. Respondents provided detailed information about the demographic characteristics of the victim (age, gender, race), characteristics of the injury (body part, nature, and type of injury), work, and causal factors. Department of Labor, Bureau of Labor Statistics, Safety and Health Statistics Program. Geneva, Switzerland: International Labour Office, Occupational Safety and Health Series No. Surveillance case definition for adult blood lead levels to be reported to the National Public Health Surveillance System. Manual of the international statistical classification of diseases, injuries, and causes of death, based on the recommendations of the Eighth Revision Conference, 1965. Manual of the international statistical classification of diseases, injuries, and causes of death, based on the recommendations of the Ninth Revision Conference, 1975. International statistical classification of diseases and related health problems, tenth revision. The information used is largely in the public domain and is available from existing bulletins, reports, or government publications. The extensive use of electronic media and the World Wide Web have increased dissemination channels for government agencies, particularly where database management systems support customization of data queries from data users. At times, users overlook or are not sensitive to aspects of data collection, analysis methods, and dissemination practices that limit the uses and inferences of data. The following information is provided to assist the users of the Chartbook and reinforce the cautionary guides that accompany the dissemination of survey and surveillance data. Fatality rates depict the risk of incurring a deadly injury faced by all or a subgroup of workers, such as workers in a certain occupation or industry. Employmentbased fatality rates measure the incidence of a fatal injury for all workers in the group regardless of exposure time.

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